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Open Source Notices

Last Updated: 2026-03-07

Dyno Therapeutics, Inc. ("Dyno," "we," "us," or "our") operates the design.dynotx.com platform. The platform incorporates open-source software and machine learning models distributed under various licenses including MIT, Apache 2.0, and Creative Commons licenses. These components remain subject to their original licenses. Dyno provides attribution where required.

Third-Party Machine Learning Models

The following models are hosted and served via the Dyno Phi API. Each model is the work of its respective authors and is subject to its original license.

ModelCitationLicense
AlphaFold2Jumper et al., Nature, 2021Apache 2.0 / CC BY 4.0
ESMFoldLin et al., Science, 2023MIT
ProteinMPNNDauparas et al., Science, 2022MIT
Boltz-1 / Boltz-2Wohlwend et al., BioRxiv 2024MIT
Chai-1Chai Discovery, BioRxiv 2024Apache 2.0
AF2RankStein & Kortemme, BioRxiv 2022MIT / Apache 2.0
ESM-2Lin et al., Science, 2023MIT
RFDiffusionWatson et al., Nature, 2023BSD-3-Clause
RFDiffusion3Institute for Protein Design / Rosetta Commons, 2025BSD-3-Clause
BoltzGenRecursion / MIT Jameel Clinic, 2024MIT
OpenFold3OpenFold Consortium / NVIDIA, 2024Apache 2.0

Platform Software

The web interface and CLI are built using the following open-source packages.

PackageLicense
Next.jsMIT
ReactMIT
Tailwind CSSMIT
shadcn/uiMIT
Framer MotionMIT
ClerkCommercial (Clerk Inc.)
ZodMIT
ShikiMIT
Lucide ReactISC

Contact

For license-related inquiries, contact legal@dynotx.com.